Importance of Malaria Vaccine. Challenges of Malaria Vaccine Essay

Importance of Malaria Vaccine. Challenges of Malaria Vaccine - Essay Example In essence, the female anopheles mosquito transmits the plasmodium parasite. According to Coleman and Tsongalis 2009, it leaves the parasite in the human blood in the process of feeding on the blood meal. However, â€Å"Anopheles gambiae, Anopheles arabiensis and Anopheles funestus†are the maintransmitters of malaria in human beings. All the malaria manifest through common symptoms like fever, although some patients progress to severe malaria that is often caused by the P. falciparum species. Essentially, it takes one to three days after infection for the infecting parasites to release the infection depending on their species. Additionally, merozoites are released through the lysis of infected erythrocytes with the inclusion of waste substances such as red membrane products, hemozoin pigments and glycosylphosphatidylinositol (GPI). The infectivity of red cells by the parasite of malaria like, P. falciparum brings about progressive together with mechanical alternation of the re d cells that can deteriorate over time into the life threatening complications of malaria Although, P.falciparum has devastatingly castigated as the major contribution to severe malaria all over the world. For instance, there have been severe infections and reports of death due to infections of P. vivax and P. knowlesi. Some pathophysilogical features like sponge biomass, reset and confiscation alter formality and restraint of parasitized erythrocyte. Endothelial activation, injury, dysfunction and altered thrombostasis have been found to entail the acquisition of severe malaria. This is common in cases of P. falciparum infection (Choffnes and Relman 2011). However, malaria’s chronicity is rare and if it happens it leads to induction of sterilizing immunity. Individuals who experience repeated exposures may be in dire need of re-exposure of the parasite if cured through drug treatment. Thus, there is a need into curbing the ease into which malaria parasite are capable of inva ding human hosts while at the same time minimizing the immune response arm (Coleman and Tsongalis 2009). Basically, two models of supporting the protection against the chances of infection of malaria through vaccination exist. The first type of vaccine entails immunization with irradiated sporozoites, which are meant to ensure maximum protection against possibility of malaria infection. The other type of vaccine entails the repeated exposure to malaria that induces immunity malaria infections and effective protection against any clinical manifestation of malaria. Importance of Malaria Vaccine Malaria has been rated among the fastest killer disease all over the world. Hence, much has to be done in order to curb the disease against causing deaths especially in infants, and the old people who have weak defence system toward diseases. In essence, malaria has not been controlled by the widespread deployment of existing control tools in most endemic areas. Moreover, there has been increas ed concern on the surfacing of insecticides and anti malarial drugs (Palmer and Reeder 2001). Vaccinations are been described as relative tools that are used to deliver and have played major roles toward the elimination of rinderpest, smallpox and other similar diseases. Never the less, the malaria vaccine is expected to provide direct individual protection against malaria infection and it clinical consequences. Additionally,, it is meant to decrease the rate of transmission of malaria infections better known as herd immunity. Immunization using Irradiated Sporozoites The possibility of giving safeguard against experimental sporozoite issues through the immunization by use of radiation attenuated sporozoites is evidenced in rodents, the natural rodents’

How the employee motivation techniques and theories currently being Dissertation

How the employee motivation techniques and theories currently being used in different organisations can be changed or improved t - Dissertation Example By examining the factors that lead to job satisfaction and dissatisfaction, the report intends to establish employee motivation techniques and strategies that organizations can employee for long term employee retention. Qualitative data was collected from employees of Standard Chartered and CO-Operative banks in the United Kingdom. The factors that made employees have job satisfaction and be motivated were explored in detail. The main focus of this study is on what sustainable measures organizations can use to motivate their employees in order to reduce employee turnover. The study was based on different motivation theories that were used to guide data collection and analysis. Table of Contents Acknowledgements 2 Abstract 3 CHAPTER ONE 1 1.0 Introduction 1 1.1Background of the Study 2 1.3 Statement of the Problem 3 1.4 Purpose of the Study 3 1.5 Research Questions 3 1.6 Research Objectives 4 CHAPTER TWO 4 2.0 Literature Review 4 2.1 Employee Retention 5 2.2 Motivation 6 2.3 Employee Motivation 6 2.4 Need Theories of Motivation 7 2.4.1 Maslow’s hierarchy of needs 7 2.4.2 Herzberg’s two factor theory 8 2.5 Equity Theory 9 2.6 Vroom’s Expectancy Theory 10 2.7Job Design 12 2.7.1 Job characteristics model 12 CHAPTER THREE 15 3.0 Research Methodology 15 3.1Research Philosophy 15 3.1.1 Positivism 15 3.1.2 Interpretivism 16 3.2 Research Design 16 3.3 Research Strategy 17 3.3.1 Case study 17   3.4 Population 18 3.5 Data Collection and Instrumentation 18 3.6 Data Analysis 19 3.7 Ethical Considerations 20 3.8 Limitations and De-limitations 21 CHAPTER FOUR 22 4.0 Data Presentation and Analysis 22 4.1 Participant Demographics 22 4.2 Job Satisfaction Factors 23 4.3 Case Study Analysis 25 CHAPTER FIVE 26 5.0 Conclusion and Recommendations 26 5.2 Recommendations 27 5.2.1 Work-life balance consideration 27 5.2.2Transformational leadership and management 27 Works Cited 28 List of Figures Figure 1: Maslow’s hierarchy of needs (Maslow, 54)†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦..8 Figure 2: Vroom’s theory of expectancy model (Vroom, 1964)†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..10 Figure 3: Job Characteristics Model of Work Motivation (Hackman & Oldham, 78).................14 Figure 4: Factors for employee motivation...................................................................................25 List of Tables Table 1: Issues to Address Concerning Employees with Regard to Expectancy Theory†¦Ã¢â‚¬ ¦.....11 Table 2: Demographics of the study participants..........................................................................23 Table 3: Response of Participants on Factors for Employee Motivation.....................................23 CHAPTER ONE 1.0 Introduction It is the goal of every organization and business to be successful and have competitive advantage in its industry. In the contemporary b usiness environment, characterized by globalization and changing demographics such as Generation Y, organizations face many challenges in their quest to remain competitive. Additionally, advances in information and communications technologies (ICT) and changing consumer patterns have driven organizations globally to adopt new organizational structures and methods of production that have greatly enhanced the mobility of people, and in turn, facilitated the rate of employee turnover. An organization’s human capital is its greatest resource and crucial to its success or failure. In most cases, qualified and well-trained staff who are committed and motivated can be a source of competitive advantage. Losing competent employees can be detrimental to the productivity of an organization. With regard to this, recruiting the right employees is a challenge, but retaining these employees is

Letter to dean Essay Example | Topics and Well Written Essays - 250 words

Letter to dean - Essay Example I believe that the highest level Economics class remains too complicated for me and any poor performance from the course would lower my overall GPA. Maintaining competitive GPA would be vital in enrolment for immediate masters’ degree. Besides the desire to maintain my GPA, my family currently faces financial constraints. My father’s company acts as the main source of income for the family and it currently faces detrimental financial challenges. The financial constraints have restrained family expenses especially my UM and apartment fee expenditures within the school. Moreover, my younger sibling would be beginning his studies in USA this year. Consequently, I would desire to graduate this semester to enable me ease the financial constraints in my family and assist my aging father in supporting us. Therefore, it is my modest plea that you grant me a permission number to enable me realizes my coveted

International Relations Essay Example | Topics and Well Written Essays - 1750 words

International Relations - Essay Example In Constructivism, human values, ideas, and shared beliefs are important because the world’s practices are constantly affected by how people speak about them (Tickner & Blaney, 2012). This theory heightens the ordinary citizen’s personal sensitivity to their socially constructed interests and identities. When considered against the backdrop of international relations, constructivism stresses on how nations perceive themselves as well as their national identity (Tickner & Blaney, 2012). Â  For instance the identification with words like ‘middle power’ or ‘superpower’ and the implied meaning that comes with these expressions determines the subject’s conduct; and so the theory’s ideas influence how states and their rulers conduct themselves on the international stage. Classical Realism and Neorealism The realism focuses on the world as it really is instead of reflecting on how it ought to be. Basically, this is an empirical and not a normative model (Tickner & Blaney, 2012). Freudian observation appear to support the realist’s beliefs in the examination of personal behaviour within groups. This seeks to define how primary human instincts lead people to engage in the avoidance of all kinds of pain, the never-ending pursuit of personal objectives, and the importance of employing foreceful tactics when dealing with other people, organizations, or nations. Realism is essentially a pessimistic theory that stresses on the intermittent patterns of power politics as evidenced by repeated rivalries, conflicts, and wars (Tickner & Blaney, 2012). In this theory, the factors that are predominant include the security dilemma and the balance of power. Realists also view the state as the main factor of importance in international affairs. The world’s superpowers or richest nations are given the most attention as they have the greatest leverage on the global stage. Additionally, it is the national interest that influences state behavior, according to this theory. Realists also maintain that the allocation of power is responsible for deciding international outcomes. Neo realism adds to realism in that it deems that international conflict is the result of the chaotic international system (Tickner & Blaney, 2012). Conversely, in neo realism, the state is not viewed as being superior to the system; which is the case in

Oppositional Defiance Essay Example | Topics and Well Written Essays - 1500 words

Oppositional Defiance - Essay Example This is exactly what transpired with the counselor who was handling Paul. She expected the good behavior presented during their initial week of interaction would continue, which prospectively will allow the child to interact with other children in a normal manner. However, this has not been the case and she became more concerned as the child’s behavior became more violent and disrupted over the next few weeks (McKurdy, 2009). Upon analysis of the case scenario, there were some plausible approaches which the counselor may have carried out in order to effectually deal with the child’s behavior. Moreover, the following pages will discuss some legal and ethical issues when the counselor agreed to isolate the child when he displayed disruptive behavior (McKurdy, 2009). First, there were some questions posed by the author at the end of the case study. The first question was if the educational needs of the child were met by the behavioral treatments given by the school administrators and the special education teachers. From my perspective, the educational needs were definitely not addressed adequately to meet the individual needs of the child. There was an excerpt where the counselor, upon the recommendation of her supervisor, placed the child on timeouts or isolation whenever he turned violent or disruptive. The child even had to spend a whole day in isolation, not being able to learn or participate in class. This punishment has even more damaging implications because the child over the next few weeks spent more time in the isolation room rather than in class (Mckurdy, 2009; Knoster, Wells, & McDowell, 2007). The second question pertained to her referral to her supervisor regarding the abrupt behavior change of Paul. The current system employed by her organization and her supervisor strictly adhered to a behavioral modification approach. As a fresh graduate who may be

Black People and Roberta Essay Example for Free

Black People and Roberta Essay In Toni Morrison’s â€Å"Recitatif,† the story is about two girls, Twyla and Roberta. They grow up in an orphanage because their mothers could not care for them. Morrison makes it clear the girls come from different ethnic backgrounds but never states which one is black or white. At one point in the story Twyla comments, â€Å"We looked like salt and pepper. † I grew frustrated with the story and had to read it several times. I could never determine who was black and white and the lesson I learned should have been it doesn’t really matter. The story begins with Twyla’s mother dropping her off at the orphanage. She meets Roberta and they become best friends. The bond they share occurs because they were not considered real orphans. They were abandoned kids unlike the other children whose parents had died. One of the last times the girls see each other was the day of a visitation. On that night, Twyla’s mother was wearing â€Å"those tight green slacks that made her butt stick out. † Many people have labeled blacks as having larger butts. She could have been black, she could have been a heavy white woman with a large butt, or a Hispanic woman like me. But I automatically stereotyped and went with Twyla has to be black. During the visitation Roberta’s mother â€Å"had brought chicken legs. † Twyla notices Roberta does not eat the chicken legs. I always thought black people liked chicken more than white people which means Roberta was white since she did not eat the chicken. Or maybe she just wasn’t hungry. Shortly after that visitation Roberta’s mother came to take her home, leaving the girls devastated. They see each other several times throughout the years. At their first meeting, Roberta was rude and distant because she was high. Roberta tells Twyla she is on the way to see Jimi Hendrix. Hendrix was an infamous black guitarist. I thought at this point Roberta has to be black. However Hendrix’s band was interracial with a diverse audience. Roberta could have been white due to the diverse audience. I am a huge Hendrix fan and I am not black so why would I think Roberta is. Twelve years later they meet again at a grocery store. Roberta married a rich man and was extremely friendly to Twyla. Twyla cannot hold back her emotions and asks Roberta about the last time they saw each other. Roberta shrugs it off, â€Å"Oh, Twyla, you know how it was in those days: black—white. You know how everything was. † I can relate to this. In 1980, the Cuban Mariel Boat Lifts came over bring thousands of Cubans. I am Cuban but I was born here. Kids I had known since kindergarten treated me as if I just come over on the boats. It had a lasting effect on me and matured me beyond my years. The third time they meet is at the school where their children attend. Roberta and other mothers were picketing because they did not want their kids to be segregated. This led to a fight severing any last chance of a friendship for them as it would not be resolved until Twyla and Roberta meet for a final time. As the story ends I do not get a sense of closure. The question of which girl is white or black remains unanswered. It opened my eyes and made me question how prejudice I really am. I try to not stereotype as a result of what I went through as a child but I found myself doing just that. I can understand why Morrison wrote the way she. I am not sure what her goal was overall but to me it seemed as if she were teaching me about prejudices. â€Å"Recitatif† challenged me to not judge either girl by their race but accept them for who they are. In the end, what difference did it really make about the girls’ races? The story is about how their friendship develops and then deteriorates. Nothing more; nothing less.

The Art of Travel Rheotrical Analysis Essay Example for Free

The Art of Travel Rheotrical Analysis Essay To begin with , every day we are surrounded by art. It dates back to ancient times, when primitive men painted on the rocks and made an instrument of labor. Actually, the meaning of this word from the Greek which means skill, ability and crafts. Apart from this, Hegel identified five great arts: architecture, sculpture, painting, music and poetry. Furthermore, along with them in the modern world there are: the theater and circus, pantomime and dance, cinema and music. According to some sources, art performs a variety of functions, but the most important, tÐ ¾ mÃ'Æ' mind, is the artistic function, which is displayed in the sensuous life and influence on the spiritual world of the man. Ð ¢Ã ¾ mÃ'Æ' way of thinking, the art is a creative interpretation of the world by man. The art has a direct relationship to the creation, accumulation and transfer of cultural values from generation to generation. After all, we are constantly learning from art. It trains our ethics, affects our feelings, will and mind. Moreover, without art, in my opinion, person simply can not exist. It seems to mÐ µ that the Art is one of the human needs. Obviously, this beauty reveals to man the path to perfection and harmony. Immortal beautiful creations of ancient sculptors and architects: Raphael, Michelangelo, Dante, Pushkin and Tolstoy, Mozart, Bach and Tchaikovsky. It will be exciting when you try to cover all created intelligence geniuses, preservation and continuation of their descendants and followers. Of course, art plays an important role in the life of human society, it ennobles people, helps people to discover themselves, to realize their dreams and ideas that enrich human life, provides a spiritual gained experience and aesthetic values. Ð ll in Ð °ll, mastering the art works, the person learns his present and future. Rejection of artistic activity can return to the original state of man, can lead to a drop of morality. If people will not appreciate art, the world is doomed to fail. Therefore, mankind must not only preserve the art, but also restore the broken and create something new, because in the words of L. N. Tolstoy: Art is a means of connecting people.